FDA-Approved Conditions


Diabetic Wounds of the Lower Extremities

Diabetes often impacts the body’s ability to heal wounds. People with diabetes are unable to metabolize glucose, leading to high blood sugar levels. Over time this can cause the following:

  • Atherosclerosis (clogged vessels) in the lower extremities

  • Peripheral Neuropathy - damage through a complex series of events that causes a breakdown to the skin of the foot

Both of these wound-causing pathways prevent oxygen rich blood flow and nutrients, which are needed to heal the wound. As a result, even a small wound can heal more slowly and worsen more quickly for diabetics.

Although cuts, blisters and scratches can occur anywhere on the body, often the feet are most impacted. A small wound on the foot can quickly develop into a foot ulcer. If left untreated, serious damage can occur. In fact, 15% to 20% of patients with wounds on the lower extremities may require lower limb amputation within 5 years. Catching wound conditions early is critically important. We encourage patients to be committed to the healing process through regular self-checks, removing dead tissue, fresh dressings and seeking medical attention for additional treatment, when needed.

Soft Tissue Radionecrosis

Soft tissue radionecrosis is a medical condition that occurs when exposure to radiation kills soft tissues in the body and tissue is unable to repair and regenerate normally. Most often this condition occurs after radiation therapy in and around the area where radiation is targeted. Injuries result from damaged capillary beds near the tumor treatment site. This reduced blood supply starves the damaged area of much needed oxygen. For wounds to heal properly, increased oxygen levels are necessary to promote healing and new growth.

Chronic Refractory Osteomyelitis

Chronic Refractory Osteomyelitis is an infection in the bone. Infections can move into the bone a number of ways.

  • Injury: An injury that exposes the bone to germs, severe puncture wounds, or an exposed bone is a risk.

  • Surgery: Contamination of germs during surgery to replace joints or repair fractures can result in osteomyelitis.

  • Bloodstream: Germs in others parts of the body can travel through the bloodstream to weakened area of the bone.

Individuals with chronic health problems, such as diabetes or kidney failure, and smokers are at increased risk of osteomyelitis. Diabetic patients are prone to developing osteomyelitis in their feet as a result of foot ulcers.